Therapeutic Areas

Tie2 is a regulator of vascular stability in the retina. Studies have shown that loss of Tie2 function is implicated in vascular compromise across all major retinopathies including: diabetic retinopathy, DME, and wet AMD.


HIF-1α is critical for the regulation of innate immune responses and maintenance of epithelial barrier function in the gastrointestinal tract. Stabilization of HIF-1α has been shown to dramatically improve wound healing and immune response in the gut.


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Diabetic Retinopathy

Wet Age Related Macular Degeneration (AMD) / Diabetic Macular Edema

Inflammatory Bowel Disease (IBD)